Chemistry:Metamfepramone

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Short description: Stimulant drug
Metamfepramone
Dimethylcathinone.svg
Clinical data
ATC code
  • none
Legal status
Legal status
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC11H15NO
Molar mass177.247 g·mol−1
3D model (JSmol)
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Metamfepramone (INN, also known as dimethylcathinone, dimethylpropion, and dimepropion (BAN)) is a stimulant drug of the phenethylamine, and cathinone chemical classes. Dimethylcathinone was evaluated as an appetite suppressant and for the treatment of hypotension, but was never widely marketed.[2]

It was used as a recreational drug in Israel under the name rakefet, but was made illegal in 2006.[3]

Metamfepramone is metabolized to produce N-methylpseudoephedrine and methcathinone.[4] It has also been found to be about 1.6 times less potent than methcathinone, making it roughly equipotent to cathinone itself.[5]

Legal Status

In the United States, metamfepramone (N,N-Dimethyl-cathinone) is considered a Schedule I controlled substance as a positional isomer of mephedrone.[6]

See also

References

  1. "Ustawa z dnia 15 kwietnia 2011 r. o zmianie ustawy o przeciwdziałaniu narkomanii ( Dz.U. 2011 nr 105 poz. 614 )". Internetowy System Aktów Prawnych. http://isap.sejm.gov.pl/DetailsServlet?id=WDU20111050614. 
  2. "[Therapy of the orthostatic syndrome. Studies using dimepropion-HCI]" (in German). Fortschritte der Medizin 100 (7): 289–293. February 1982. PMID 7042502. 
  3. "Recreational drug 'rakefet' banned". The Jerusalem Post. 22 February 2006. https://www.jpost.com/Health-and-Sci-Tech/Health/Recreational-drug-rakefet-banned. 
  4. "Doping control analysis of metamfepramone and two major metabolites using liquid chromatography-tandem mass spectrometry". European Journal of Mass Spectrometry 15 (4): 507–515. 2009. doi:10.1255/ejms.1010. PMID 19661559. 
  5. "Cathinone: an investigation of several N-alkyl and methylenedioxy-substituted analogs". Pharmacology, Biochemistry, and Behavior 58 (4): 1109–1116. December 1997. doi:10.1016/s0091-3057(97)00323-7. PMID 9408221. 
  6. "Orange Book - List of Controlled Substances and Regulated Chemicals". https://www.deadiversion.usdoj.gov/schedules/orangebook/orangebook.pdf.