Chemistry:2C-T-3

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2C-T-3
2C-T-3.svg
Names
Preferred IUPAC name
2-{2,5-Dimethoxy-4-[(2-methylprop-2-en-1-yl)sulfanyl]phenyl}ethan-1-amine
Identifiers
3D model (JSmol)
Properties
C14H21NO2S
Molar mass 267.39 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

2C-T-3 (also initially numbered as 2C-T-20) is a lesser-known psychedelic drug related to compounds such as 2C-T-7 and 2C-T-16. It was named by Alexander Shulgin but was never made or tested by him, and was instead first synthesised by Daniel Trachsel some years later. It has a binding affinity of 11nM at 5-HT2A and 40nM at 5-HT2C. It is reportedly a potent psychedelic drug with an active dose in the 15–40 mg range, and a duration of action of 8–14 hours, with visual effects comparable to related drugs such as methallylescaline.[1][2][3]

See also

References

  1. "Synthesis of novel (phenylalkyl)amines for the investigation of structure-activity relationships. Part 2. 4-Thio-substituted [2-(2,5-dimethoxyphenyl)ethyl]amines (=2,5-dimethoxybenzeneethanamines)". Helvetica Chimica Acta 86 (7): 2610–2619. 2003. doi:10.1002/hlca.200390210. 
  2. "Monoamine receptor interaction profiles of 4-thio-substituted phenethylamines (2C-T drugs)". Neuropharmacology 134 (Pt A): 141–148. May 2018. doi:10.1016/j.neuropharm.2017.07.012. PMID 28720478. https://edoc.unibas.ch/57358/1/20170920150712_59c2680084ec5.pdf. 
  3. Phenethylamine: Von der Struktur zur Funktion. Nachtschatten Verlag AG. 2013. pp. 788–794. ISBN 978-3-03788-700-4.