Chemistry:Para-Bromoamphetamine

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Short description: Chemical compound


para-Bromoamphetamine
4-bromoamphetamine.svg
4-BA44.jpg
Clinical data
ATC code
  • none
Legal status
Legal status
  • DE: NpSG (Industrial and scientific use only)
  • UK: Class A
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
Chemical and physical data
FormulaC9H12BrN
Molar mass214.106 g·mol−1
3D model (JSmol)
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para-Bromoamphetamine (PBA), also known as 4-bromoamphetamine (4-BA), is an amphetamine derivative which acts as a serotonin-norepinephrine-dopamine releasing agent (SNDRA) and produces stimulant effects.

Another related compound is para-bromomethamphetamine known by the codename V-111.[1]

Neurotoxicity

Like most other para-substituted amphetamines, PBA can be neurotoxic and may deplete the brain of 5-hydroxyindoles for at least a week.[2]

See also

References

  1. "The fate of p-bromo-methylamphetamine (V-111) in the body". Acta Physiologica Academiae Scientiarum Hungaricae 57 (3): 285–307. 1981. PMID 7304194. 
  2. "Comparison of 4-chloro-, 4-bromo- and 4-fluoroamphetamine in rats: drug levels in brain and effects on brain serotonin metabolism". Neuropharmacology 14 (10): 739–46. October 1975. doi:10.1016/0028-3908(75)90099-4. PMID 1196472.