Chemistry:Hexacyclonate

From HandWiki
Short description: Chemical compound
Hexacyclonate
Hexacyclonate.svg
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
Chemical and physical data
FormulaC9H16O3
Molar mass172.222 g·mol−1
3D model (JSmol)
  (verify)

Hexacyclonate (Gevilon) is a stimulant drug. It has been used for the treatment of alcoholism[1] and for increasing motivation in elderly patients,[2] but Gevilon (containing a different active substance - gemfibrozil) is now mainly used for the treatment of hyperlipoproteinaemia.[3][4] It is chemically similar to the anticonvulsant gabapentin, with a hydroxyl group replacing the amine.

The latter use may be incorrectly assigned, as "Gevilon" has been used as a trade name for gemfibrozil, a well-known drug for dislypidemia.

References

  1. "Adjunctive treatment of the chronic alcoholic with hexacyclonate sodium". The Illinois Medical Journal 121: 546–8. May 1962. PMID 13878809. 
  2. "Pharmaco-motivation of the geriatric patient: a preliminary report on hexacyclonate". The Journal of the Louisiana State Medical Society 114: 23–6. January 1962. PMID 14476295. 
  3. "Therapeutic effect of gevilon in patients with hyperlipoproteinaemia". Materia Medica Polona. Polish Journal of Medicine and Pharmacy 24 (2): 91–5. 1992. PMID 1307777. 
  4. "Pharmacoeconomic aspects of patients treated by hemodialysis". Bratislavske Lekarske Listy 104 (10): 329–34. 2003. PMID 15055734.