Chemistry:3-Fluoroethamphetamine
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Short description: Stimulant drug of the amphetamine class
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| Formula | C11H16FN |
| Molar mass | 181.254 g·mol−1 |
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3-Fluoroethamphetamine (3-FEA) is a stimulant drug of the amphetamine class which acts as a releasing agent of the monoamine neurotransmitters norepinephrine, dopamine and serotonin.
Compared to the unsubstituted ethylamphetamine, 3-fluoroethamphetamine is a weaker releaser of noradrenaline, but a stronger releaser of both dopamine and serotonin, and produced the strongest reinforcing effects in animal studies out of a range of 3-substituted ethamphetamine derivatives tested, despite not being the most potent dopamine releaser.[1][2][3][4]
See also
- 2-Fluoroamphetamine
- 2-Fluoromethamphetamine
- 3-Fluoroamphetamine
- 3-Fluoromethamphetamine
- 4-Fluoroamphetamine
- 4-Fluoromethamphetamine
- Fenfluramine
References
- ↑ "Structural relationship between meta-substituted N-ethylamphetamines and self-administration in rhesus monkeys.". Pharmacologist 16: 142. 1974.
- ↑ "Structure-activity relationships between meta-substituted N-ethylamphetamines and locomotor activity in mice". The Journal of Pharmacology and Experimental Therapeutics 192 (2): 310–8. February 1975. PMID 1117418.
- ↑ "Specificity of release of biogenic amines from isolated rat brain tissue as a function of the meta substituent of N-ethylamphetamine derivatives". The Journal of Pharmacology and Experimental Therapeutics 197 (2): 253–62. May 1976. PMID 1271279.
- ↑ "meta Substituted N-ethylamphetamine self injection responding in the rhesus monkey: structure-activity relationships". The Journal of Pharmacology and Experimental Therapeutics 205 (2): 274–81. May 1978. PMID 417172.
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