Chemistry:Alpha-Difluoromethyl-DOPA

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α-Difluoromethyl-DOPA
Skeletal formula
Ball-and-stick model of α-difluoromethyl-DOPA
Names
Preferred IUPAC name
(2S)-2-Amino-2-[(3,4-dihydroxyphenyl)methyl]-3,3-difluoropropanoic acid
Identifiers
3D model (JSmol)
ChemSpider
MeSH alpha-difluoromethyl-DOPA
UNII
Properties
C10H11F2NO4
Molar mass 247.20 g/mol
Density 1.528 g/mL
Boiling point 479 °C (894 °F; 752 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

α-Difluoromethyl-DOPA (DFMD, DFM-DOPA) is a DOPA decarboxylase inhibitor.[1]

See also

References

  1. "Inhibition of 5-hydroxytryptophan nephrotoxicity by alpha-difluoromethyl-dopa, an inhibitor or L-amino acid decarboxylase". Toxicology Letters 5 (2): 125–9. February 1980. doi:10.1016/0378-4274(80)90161-7. PMID 6781106.