Chemistry:Codoxime

From HandWiki
Short description: Chemical compound
Codoxime
Codoxime.svg
Clinical data
Other namesCodoxime
ATC code
  • none
Legal status
Legal status
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
Chemical and physical data
FormulaC20H24N2O5
Molar mass372.421 g·mol−1
3D model (JSmol)

Codoxime (Codossima) is an opiate analogue that is a derivative of hydrocodone, where the 6-ketone group has been replaced by carboxymethyloxime. It has primarily antitussive effects[1] and was found to have moderate potential to cause dependence in animal studies.[2]

References

  1. Jack Fishman, "Morphinone and Codeinone Derivatives", US patent granted 3153042, issued 13 October 1964, assigned to Mozes Juda Lowenstein
  2. "Assessment of the dependence-producing properties of dihydrocodeinone and codoxime". Clinical Pharmacology and Therapeutics 8 (2): 266–70. 1967. doi:10.1002/cpt196782266. PMID 6021586.