Chemistry:Eptazocine

From HandWiki
Short description: Opioid analgesic
Eptazocine
Skeletal formula
Ball-and-stick model
Clinical data
Routes of
administration
Oral
ATC code
  • None
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
Chemical and physical data
FormulaC15H21NO
Molar mass231.339 g·mol−1
3D model (JSmol)

Eptazocine (Sedapain) is an opioid analgesic which was introduced in Japan by Morishita in 1987.[1][2][3][4] It acts as a mixed κ-opioid receptor agonist and μ-opioid receptor antagonist.[4][5][6]

See also

  • Benzomorphan

References

  1. Index nominum 2000: international drug directory. Taylor & Francis US. 2000. p. 396. ISBN 978-3-88763-075-1. https://books.google.com/books?id=5GpcTQD_L2oC&pg=PA396. Retrieved 29 November 2011. 
  2. American Chemical Society. Division of Medicinal Chemistry (1990). "Cumulative NCE Introduction index, 1983-189, by Indication". Annual Reports in Medicinal Chemistry. Academic Press. p. 381. ISBN 978-0-12-040525-1. https://books.google.com/books?id=NZZbEkldeJAC&pg=PA381. Retrieved 29 November 2011. 
  3. "The interaction of eptazocine, a novel analgesic, with opioid receptors". Research Communications in Chemical Pathology and Pharmacology 48 (2): 173–181. May 1985. PMID 2992058. 
  4. 4.0 4.1 "Synthesis of Novel Basic Skeletons Derived from Naltrexone". Chemistry of Opioids. Springer. 21 January 2011. p. 280. ISBN 978-3-642-18106-1. https://books.google.com/books?id=5GUn9E-9irMC&pg=PA280. Retrieved 29 November 2011. 
  5. "[Preferential action of eptazocine, a novel analgesic, with opioid receptors in isolated guinea pig ileum and mouse vas deferens preparations]" (in ja). Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica 95 (1): 41–46. January 1990. doi:10.1254/fpj.95.1_41. PMID 2154395. 
  6. Concise dictionary of pharmacological agents: properties and synonyms. Springer. 1999. p. 113. ISBN 978-0-7514-0499-9. https://books.google.com/books?id=mqaOMOtk61IC&pg=PA113. Retrieved 29 November 2011.