Chemistry:Butyrylnorfentanyl

From HandWiki
Short description: Synthetic opioid analgesic metabolite


Butyrylnorfentanyl
Butyrylnorfentanyl.svg
Butyrylnorfentanyl 3D BS.png
Identifiers
CAS Number
PubChem CID
ChemSpider
Chemical and physical data
FormulaC15H22N2O
Molar mass246.354 g·mol−1
3D model (JSmol)

Butyrnorfentanyl or butyrylnorfentanyl is an inactive synthetic opioid analgesic drug precursor. It is an analog of fentanyl.[1][2][3][4][5][6][7][8][9][10]

See also

References

  1. Strayer, Kraig E. (2018). "LC-MS/MS-based method for the multiplex detection of 24 fentanyl analogues and metabolites in whole blood at sub ng mL–1 concentrations.". ACS Omega 3 (1): 514–523. doi:10.1021/acsomega.7b01536. PMID 29399650. 
  2. Mannocchi, Giulio (2020). "Development and validation of fast UHPLC-MS/MS screening method for 87 NPS and 32 other drugs of abuse in hair and nails: application to real cases.". Analytical and Bioanalytical Chemistry 412 (21): 5125–5145. doi:10.1007/s00216-020-02462-6. PMID 32062830. 
  3. Freni, Francesca (2020). "Determination of fentanyl and 19 derivatives in hair: application to an Italian population.". Journal of Pharmaceutical and Biomedical Analysis 189: 113476. doi:10.1016/j.jpba.2020.113476. PMID 32693203. 
  4. Lanzarotta, Adam (2020). "Identification of opioids and related substances using handheld Raman spectrometers.". Journal of Forensic Sciences 65 (2): 421–427. doi:10.1111/1556-4029.14217. PMID 31643087. 
  5. Larabi, Islam Amine (2020). "Development and validation of liquid chromatography-tandem mass spectrometry targeted screening of 16 fentanyl analogs and U-47700 in hair: Application to 137 authentic samples". Drug Testing and Analysis 12 (9): 1298–1308. doi:10.1002/dta.2868. PMID 32476263. 
  6. Strayer, Kraig Edward (2018). A LC-MS/MS-Based Method for the Multiplex Detection of 24 Fentanyl Analogs and Metabolites in Whole Blood at Sub ng mL-1 Concentrations.. 
  7. Vaiano, Fabio (2021). "Development of a new LC-MS/MS screening method for detection of 120 NPS and 43 drugs in blood.". Separations 8 (11): 221. doi:10.3390/separations8110221. 
  8. Kern, Sara. "Rapid-field-deployable DART-MS screening technique for 87 opioids and drugs of abuse, including fentanyl and fentanyl analogs.". Journal of Regulatory Science 10 (2). 
  9. Garneau, Béatrice (2021). "A comprehensive analytical process, from NPS threat identification to systematic screening: method validation and one-year prevalence study.". Forensic Science International 318: 110595. doi:10.1016/j.forsciint.2020.110595. PMID 33279767. 
  10. Carelli, Claudia (2022). "Old and New Synthetic and Semi-synthetic Opioids Analysis in Hair: A Review.". Talanta Open 100108. 

Further reading

  • "Studies on 1-(2-phenethyl)-4-(N-propionylanilino)piperidine (fentanyl) and its related compounds. VI. Structure-analgesic activity relationship for fentanyl, methyl-substituted fentanyls and other analogues". Forensic Toxicology 26 (1): 1–5. June 2008. doi:10.1007/s11419-007-0039-1. 
  • "Fentanyl receptor assay. II. Utilization of a radioreceptor assay for the analysis of fentanyl analogs in urine". J Anal Toxicol 16 (1): 36–41. 1992. doi:10.1093/jat/16.1.36. PMID 1322477. 
  • "Evaluation of new compounds for opioid activity: 1987 annual report". NIDA Res. Monogr. 81: 543–90. 1988. PMID 3136388. 
  • "Dependence studies of new compounds in the rhesus monkey, rat, and mouse, 1987". NIDA Res. Monogr. 81: 485–542. 1988. PMID 3136386. 
  • "Carbon-13 nuclear magnetic resonance spectra of fentanyl analogs". Journal of Heterocyclic Chemistry 26 (3): 677–686. 2009. doi:10.1002/jhet.5570260329.