Chemistry:Estradiol furoate

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Short description: Chemical compound
Estradiol furoate
Estradiol furoate.svg
Clinical data
Trade namesDi-Folliculine
Other namesEF; 17-Furoylestradiol; 17-(2-Furancarbonyl)estradiol
Routes of
administration
Intramuscular injection
Drug classEstrogen; Estrogen ester
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC23H26O4
Molar mass366.457 g·mol−1
3D model (JSmol)

Estradiol furoate (EF), or estradiol 17β-furoate, sold under the brand name Di-Folliculine, is an estrogen medication and estrogen ester which is no longer marketed.[1] It is the C17β furoate ester of estradiol.[1] Estradiol benzoate has also been marketed under the brand name Di-Folliculine, and should not be confused with estradiol furoate.[2]

The duration of action of the related estradiol ester estradiol 3-furoate by intramuscular injection was studied in women in 1952.[3] Its duration in oil solution was found to be similar to that of estradiol benzoate in oil solution and shorter than that of estradiol dipropionate in oil solution.[3]

See also

References

  1. 1.0 1.1 The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. 14 November 2014. p. 898. ISBN 978-1-4757-2085-3. https://books.google.com/books?id=0vXTBwAAQBAJ&pg=RA1-PA129. 
  2. Pharmaceutical Abstracts. American Pharmaceutical Association.. 1941. p. 149. https://books.google.com/books?id=spLyAAAAMAAJ. 
  3. 3.0 3.1 "Relative duration of action of natural and synthetic estrogens administered parenterally in women with estrogen deficiency". The Journal of Clinical Endocrinology and Metabolism 12 (1): 28–35. January 1952. doi:10.1210/jcem-12-1-28. PMID 14907837.