Chemistry:Deoxyadenosine
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| Names | |
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| IUPAC name
(2R,3S,5R)-5-(6-Amino-9H-purin-9-yl)-2-(hydroxymethyl)oxolan-3-ol
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| Other names
2′-Deoxyadenosine; α-Deoxyadenosine; dA
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| Identifiers | |
3D model (JSmol)
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| ChEBI | |
| ChEMBL | |
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| MeSH | 2'-deoxyadenosine |
PubChem CID
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| Properties | |
| C10H13N5O3 | |
| Molar mass | 251.24192 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
 verify (what is   ?)
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| Infobox references | |
Tracking categories (test):
Deoxyadenosine (symbol dA or dAdo) is a deoxyribonucleoside. It is a derivative of the nucleoside adenosine, differing from the latter by the replacement of a hydroxyl group (-OH) by hydrogen (-H) at the 2′ position of its ribose sugar moiety. Deoxyadenosine is the DNA nucleoside A, which pairs with deoxythymidine (T) in double-stranded DNA.
In absence of adenosine deaminase (ADA) it accumulates in T lymphocytes and kills these cells resulting in a genetic disorder known as adenosine deaminase severe combined immunodeficiency disease (ADA-SCID).[1]
See also
- Deoxyribonucleotide
- Cordycepin (3′-deoxyadenosine)
- Severe combined immunodeficiency
References
- ↑ Griffiths, Anthony J. F.; Wessler, Susan R.; Carroll, Sean B.; Doebly, John (2012). Introduction to Genetic Analysis (10th ed.). New York: W . H. Freeman and Company. ISBN 978-1-4641-0661-3.
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