Biology:TAS2R4

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A representation of the 3D structure of the protein myoglobin showing turquoise α-helices.
Generic protein structure example

Taste receptor type 2 member 4 is a protein that in humans is encoded by the TAS2R4 gene.[1][2][3]

Function

This gene encodes a member of a family of candidate taste receptors that are members of the G protein-coupled receptor superfamily and that are specifically expressed by taste receptor cells of the tongue and palate epithelia. These apparently intronless genes encode a 7-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is clustered with another 3 candidate taste receptor genes in chromosome 7 and is genetically linked to loci that influence bitter perception.[3]

See also

References

  1. "A novel family of mammalian taste receptors". Cell 100 (6): 693–702. Apr 2000. doi:10.1016/S0092-8674(00)80705-9. PMID 10761934. 
  2. "T2Rs function as bitter taste receptors". Cell 100 (6): 703–11. Apr 2000. doi:10.1016/S0092-8674(00)80706-0. PMID 10761935. 
  3. 3.0 3.1 "Entrez Gene: TAS2R4 taste receptor, type 2, member 4". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=50832. 

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.