Biology:FZD1

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A representation of the 3D structure of the protein myoglobin showing turquoise α-helices.
Generic protein structure example

Frizzled-1 is a protein that in humans is encoded by the FZD1 gene.[1][2]

Function

Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD1 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-terminal PDZ domain-binding motif. The FZD1 transcript is expressed in various tissues.[2]

See also

References

  1. "Molecular cloning, differential expression, and chromosomal localization of human frizzled-1, frizzled-2, and frizzled-7". Biochemical and Biophysical Research Communications 252 (1): 117–22. Nov 1998. doi:10.1006/bbrc.1998.9607. PMID 9813155. 
  2. 2.0 2.1 "Entrez Gene: FZD1 frizzled homolog 1 (Drosophila)". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8321. 

Further reading

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.