Chemistry:Stearoylethanolamide

From HandWiki
Stearoylethanolamide
Stearoylethanolamide.svg
Names
IUPAC name
N-(2-Hydroxyethyl)octadecanamide
Identifiers
3D model (JSmol)
ChemSpider
UNII
Properties
C20H41NO2
Molar mass 327.553 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
Tracking categories (test):

Stearoylethanolamide (SEA) is an endocannabinoid neurotransmitter.[1]

Stearoylethanolamide (C20H41NO2; 18:0), also called N-(octadecanoyl)ethanolamine, is an N-acylethanolamine and the ethanolamide of octadecanoic acid (C18H36O2; 18:0) and ethanolamine (MEA: C2H7NO), and functionally related to an octadecanoic acid.[2]

Levels of SEA correlate with changes in pain intensity, indicating this SEA change, reflect the pain reduction effects of IPRP.[3]

References

  1. Mauro Maccarrone, Riccardo Pauselli, Marianna Di Rienzo, Alessandro Finazzi-Agrò (2002). "Binding, degradation and apoptotic activity of stearoylethanolamide in rat C6 glioma cells". Biochem J 366 (Pt 1): 137–144. doi:10.1042/BJ20020438. PMID 12010121. 
  2. PubChem. "N-(2-Hydroxyethyl)octadecanamide" (in en). https://pubchem.ncbi.nlm.nih.gov/compound/27902. 
  3. Stensson, Niclas; Gerdle, Björn; Rönne-Petersén, Linn; Yang, Liu L.; Lavebratt, Catharina; Falkenberg, Torkel; Ghafouri, Bijar (2022-02-26). "Investigating the Long-Term Effect of an Interdisciplinary Multimodal Rehabilitation Program on Levels of Bioactive Lipids and Telomerase Activity in Blood from Patients with Chronic Pain". Journal of Clinical Medicine 11 (5): 1291. doi:10.3390/jcm11051291. ISSN 2077-0383. PMID 35268382.