Chemistry:Tetrazolylglycine
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| IUPAC name
(RS)-Amino(1H-tetrazol-5-yl)acetic acid
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3D model (JSmol)
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| Properties | |
| C3H5N5O2 | |
| Molar mass | 143.106 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
 verify (what is   ?)
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Tracking categories (test):
Tetrazolylglycine (Tet-Gly, LY-285,265) is a potent and selective NMDA receptor agonist, stimulating the NMDA receptor with higher potency than either glutamate or NMDA.[1] It is a potent convulsant and excitotoxin and is used in scientific research.[2][3]
References
- ↑ "DL-tetrazol-5-ylglycine, a highly potent NMDA agonist: its synthesis and NMDA receptor efficacy". Journal of Medicinal Chemistry 35 (24): 4608–12. 1992. doi:10.1021/jm00102a015. PMID 1361579.
- ↑ "D,L-(tetrazol-5-yl) glycine: a novel and highly potent NMDA receptor agonist". European Journal of Pharmacology 203 (2): 237–43. 1991. doi:10.1016/0014-2999(91)90719-7. PMID 1686860.
- ↑ "The NMDA receptor agonist DL-(tetrazol-5-yl)glycine is a highly potent excitotoxin". European Journal of Pharmacology 270 (1): 67–72. 1994. doi:10.1016/0926-6917(94)90081-7. PMID 8157082.
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