Chemistry:Oxotremorine

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Short description: Chemical compound
Oxotremorine
Oxotremorine.svg
Clinical data
Pregnancy
category
  • C
Routes of
administration
Oral, intravenous
ATC code
  • none
Legal status
Legal status
  • US: Experimental/not yet approved
Identifiers
CAS Number
IUPHAR/BPS
ChemSpider
UNII
ChEMBL
Chemical and physical data
FormulaC12H18N2O
Molar mass206.28 g·mol−1
3D model (JSmol)
 ☒N☑Y (what is this?)  (verify)

Oxotremorine is a drug that acts as a selective muscarinic acetylcholine receptor agonist.[1]

Oxotremorine produces ataxia, tremor and spasticity, similar to those symptoms seen in Parkinsonism, and has thus become a research tool in experimental studies aimed at determining more effective anti-Parkinsonian drugs.[2]

Oxotremorine also produces antipsychotic effects.[3]

References

  1. "Effects of the muscarinic agonist oxotremorine on membrane fluidity in rat lymphocytes". Biochemistry and Molecular Biology International 29 (6): 1047–54. April 1993. INIST:4025194. PMID 8330013. 
  2. Modern Pharmacology with Clinical Applications. Lippincott Williams & Wilkins. 2004. ISBN 978-0-7817-3762-3. [page needed]
  3. "Antipsychotic property of a muscarinic receptor agonist in animal models for schizophrenia". Pharmacology, Biochemistry, and Behavior 91 (1): 140–9. November 2008. doi:10.1016/j.pbb.2008.06.023. INIST:20678587. PMID 18651995. 

See also