Chemistry:Estradiol 17β-acetate

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Short description: Chemical compound
Estradiol 17β-acetate
Estradiol acetate.svg
Clinical data
Drug classEstrogen; Estrogen ester
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
Chemical and physical data
FormulaC20H26O3
Molar mass314.425 g·mol−1
3D model (JSmol)

Estradiol 17β-acetate is an estrogen and an estrogen ester—specifically, the C17β acetate ester of estradiol—which was never marketed.[1][2][3] It is the C17β positional isomer of the better-known and clinically used estradiol ester estradiol acetate (estradiol 3-acetate; Femtrace).[1]


See also

References

  1. 1.0 1.1 "Chemie und Pharmakologie von Steroidhormon-Estern" (in de). Z Vitam Horm Fermentforsch 9 (1–2): 97–143 contd. 1957. PMID 13531579. 
  2. "The interaction of C-17 esters of estradiol with the estrogen receptor". Endocrinology 114 (4): 1180–6. April 1984. doi:10.1210/endo-114-4-1180. PMID 6705734. 
  3. "Role of pocket flexibility in the modulation of estrogen receptor alpha by key residue arginine 394". Environ. Toxicol. Chem. 30 (2): 330–6. February 2011. doi:10.1002/etc.389. PMID 21038436.