Chemistry:Ceronapril

Ceronapril
Clinical data
AHFS/Drugs.com	Monograph
ATC code	C09AA09 (WHO) ;
Identifiers
	IUPAC name 1-[(2S)-6-Amino-2-hydroxyhexanoyl]-L-proline, hydrogen (4-phenyl-butyl)phosphonate;
CAS Number	111223-26-8;
PubChem CID	189729;
ChemSpider	164789;
UNII	X3MM60SOVP;
KEGG	D03440;
Chemical and physical data
Formula	C30H46NO7P
Molar mass	563.672 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C1C[C@H](N(C1)C(=O)[C@H](CCCCN)OP(=O)(CCCCC2=CC=CC=C2)O)C(=O)O;
	InChI InChI=1S/C30H46NO7P/c1-4-28(33)37-30(22(2)3)38-39(36,18-12-11-15-23-13-7-5-8-14-23)21-27(32)31-20-25(19-26(31)29(34)35)24-16-9-6-10-17-24/h5,7-8,13-14,22,24-26,30H,4,6,9-12,15-21H2,1-3H3,(H,34,35)/t25-,26+,30?,39-/m1/s1 ; Key:BIDNLKIUORFRQP-YYTCENNOSA-N ;

Short description: Chemical compound

Ceronapril (INN,^[1] proposed trade names Ceranapril, Novopril) is a phosphonate ACE inhibitor^[2] that was never marketed.^{[citation needed]}

References

↑ "International Nonproprietary Names for Pharmaceutical Substances (INN). Recommended International Nonproprietary Names (Rec. INN): List 31". World Health Organization. p. 4. https://www.who.int/medicines/publications/druginformation/innlists/RL31.pdf.
↑ "Radioimmunoassay for ceronapril, a new angiotensin-converting enzyme inhibitor, and its application to a pharmacokinetic study in healthy male volunteers". Therapeutic Drug Monitoring 14 (3): 209–19. June 1992. doi:10.1097/00007691-199206000-00007. PMID 1412607.

0.00

(0 votes)

Original source: https://en.wikipedia.org/wiki/Ceronapril. Read more

[INN-1] "International Nonproprietary Names for Pharmaceutical Substances (INN). Recommended International Nonproprietary Names (Rec. INN): List 31". World Health Organization. p. 4. https://www.who.int/medicines/publications/druginformation/innlists/RL31.pdf.

[2] "Radioimmunoassay for ceronapril, a new angiotensin-converting enzyme inhibitor, and its application to a pharmacokinetic study in healthy male volunteers". Therapeutic Drug Monitoring 14 (3): 209–19. June 1992. doi:10.1097/00007691-199206000-00007. PMID 1412607.

[1]

[2]

v t e Antihypertensives: agents acting on the renin–angiotensin system (C09)
ACE inhibitors ("-pril")	Sulfhydryl-containing: Captopril Rentiapril Zofenopril Dicarboxylate-containing: Enalapril<sup># Benazepril Cilazapril Delapril Imidapril Lisinopril (+HCT) Moexipril Perindopril (+indapamide) Quinapril (+HCT) Ramipril Spirapril Temocapril Trandolapril Phosphonate-containing: Ceronapril Fosinopril (+HCT) Other/ungrouped: Alacepril
AIIRAs ("-sartan")	Azilsartan Candesartan Eprosartan Fimasartan Irbesartan Losartan (+HCT) Olmesartan (+amlodipine) Tasosartan^§ Telmisartan (+HCT) Valsartan (+HCT, +amlodipine)
Renin inhibitors ("-kiren")	Aliskiren (+amlodipine, +amlodipine and HCT) Remikiren^§
Dual ACE/NEP inhibitors	Gemopatrilat Ilepatril Omapatrilat Sampatrilat
Neprilysin inhibitors	Sacubitril (+valsartan)
^#WHO-EM ^‡Withdrawn from market Clinical trials: ^†Phase III ^§Never to phase III

Anonymous

Search

Chemistry:Ceronapril

Namespaces

More

Page actions

References

Navigation

Navigation

Help

Translate

Wiki tools

Wiki tools

Anonymous

Search

Chemistry:Ceronapril

References

Navigation

Wiki tools

Page tools

Other projects

Categories