Chemistry:Balofloxacin

From HandWiki
Short description: Chemical compound
Balofloxacin
Balofloxacin structure.svg
Clinical data
ATC code
  • none
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
Chemical and physical data
FormulaC20H24FN3O4
Molar mass389.427 g·mol−1
3D model (JSmol)
 ☒N☑Y (what is this?)  (verify)

Balofloxacin (INN) is a fluoroquinolone antibiotic. It is sold under the brand name Q-Roxin in Korea, and under various names in India.[1] It is not approved by the FDA for use in the United States.

Pharmacodynamics

Balofloxacin is a fluoroquinolone that has a broad spectrum in vitro activity against a wide range of Gram-positive and Gram-negative bacteria, with enhanced activity against Gram positive bacteria, including MRSA and Streptococcus pneumoniae.[2] It functions by inhibiting the action of DNA-gyrase, preventing bacterial cells from reproducing or repairing themselves, resulting in cellular death.[3]

Side Effects

Vomiting, headache, dizziness, stomach pain, nausea, diarrhea and decreased liver function are the most common side effects. In rare cases, Balofloxacin can lead to or worsen tendinitis,[3] and muscular damage.[3]

See also

  • Quinolones

References