Biology:Chlormadinone caproate

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Short description: Chemical compound
Chlormadinone caproate
Chlormadinone caproate.svg
Clinical data
Other namesCMC; Chlormadinone hexanoate; 6-Chloro-17α-hydroxy-Δ6-progesterone hexanoate; 6-Chloro-17α-hydroxypregna-4,6-diene-3,20-dione hexanoate
Routes of
administration
Intramuscular injection
Drug classProgestogen; Progestin; Progestogen ester
Identifiers
CAS Number
UNII
Chemical and physical data
FormulaC27H37ClO4
Molar mass461.04 g·mol−1
3D model (JSmol)

Chlormadinone caproate (CMC) is a progestin and a progestogen ester which was studied for potential use in combined injectable contraceptives but was never marketed.[1][2][3][4] It was assessed in combination with estradiol valerate at doses of 80 mg and 3 mg, respectively.[1][2][3] In addition to chlormadinone acetate (CMA), analogues of CMC include gestonorone caproate, hydroxyprogesterone caproate, medroxyprogesterone caproate, megestrol caproate, and methenmadinone caproate.[5]

See also

References

  1. 1.0 1.1 Daniel R. Mishell (1983). Long-acting Steroid Contraception. Raven Press. pp. 69, 77. ISBN 978-0-89004-932-7. https://books.google.com/books?id=upNsAAAAMAAJ. 
  2. 2.0 2.1 "Existing once-a-month combined injectable contraceptives". Contraception 49 (4): 293–301. April 1994. doi:10.1016/0010-7824(94)90029-9. PMID 8013216. 
  3. 3.0 3.1 "A review of "once-a-month" combined injectable contraceptives". J Obstet Gynaecol (Lahore) 4 (Suppl 1): S1–34. 1994. doi:10.3109/01443619409027641. PMID 12290848. 
  4. "GLC determination of chlormadinone acetate in plasma". J Pharm Sci 61 (9): 1441–4. September 1972. doi:10.1002/jps.2600610919. PMID 4115914. 
  5. Bouchard, P. (2005). "Chlormadinone acetate (CMA) in oral contraception--a new opportunity". The European Journal of Contraception & Reproductive Health Care 10 (Suppl 1): 7–11. doi:10.1080/13625180500434889. ISSN 1362-5187. PMID 16356876. https://pubmed.ncbi.nlm.nih.gov/16356876/.