Chemistry:Chlormethenmadinone acetate

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Short description: Chemical compound
Chlormethenmadinone acetate
Chlormethenmadinone acetate.svg
Clinical data
Trade namesBiogest, Sterolibrin, Antigest B, Agelin
Other namesSCH-12600; 6-Chloromethylene­dehydroacetoxy­progesterone; 17α-Acetoxy-6-chloro-16-methylene-6-dehydroprogesterone; 16-Methylene­chlormadinone acetate; 17α-Acetoxy-6-chloro-16-methylenepregna-4,6-diene-3,20-dione
Drug classProgestogen; Progestin; Progestogen ester
Identifiers
CAS Number
PubChem CID
ChemSpider
ChEMBL
Chemical and physical data
FormulaC24H29ClO4
Molar mass416.94 g·mol−1
3D model (JSmol)

Chlormethenmadinone acetate (CMMA), also known as chlorsuperlutin, is a progestin medication which was developed in Czechoslovakia in the 1960s.[1] It has been used in combination with mestranol in birth control pills under the brand names Biogest, Sterolibrin, and Antigest B,[2][3] and in veterinary medicine under the brand name Agelin.[4] Analogues of CMMA include bromethenmadinone acetate (bromsuperlutin), which was assessed but was never marketed,[3][5] and melengestrol acetate (methylsuperlutin), which is used in veterinary medicine.[6]

See also

References

  1. "New biological application of contraceptive steroids.". Endocrinologia Experimentalis 2 (2): 101–110. 1968. https://www.popline.org/node/469522. 
  2. "[Biogest"] (in cs). Casopis Lekaru Ceskych 111 (30): 694–695. July 1972. PMID 5079918. https://www.popline.org/node/482986. Retrieved 2018-09-16. 
  3. 3.0 3.1 "[Towards a more physiological hormonal contraception"] (in de). Zentralblatt Fur Gynakologie 92 (10): 303–312. March 1970. PMID 4096927. https://www.popline.org/node/470458. Retrieved 2018-09-16. 
  4. "[Thyroid and ovarian hormones in ewes treated with gestagens and PMSG in the spring season"] (in sk). Veterinarni Medicina 40 (11): 345–352. November 1995. PMID 8659087. https://vetmed.vri.cz/?page=abstracts&detail=321. Retrieved 2018-09-16. 
  5. Štěrba, R. (1971). "On the Way to a More Physiological Hormonal Contraception". Current Problems in Fertility. pp. 154–158. doi:10.1007/978-1-4615-8651-7_28. ISBN 978-1-4615-8653-1. https://www.popline.org/node/480951. Retrieved 2018-09-16. 
  6. "Über neue Arzneimittel". Fortschritte der Arzneimittelforschung / Progress in Drug Research / Progrès des recherches pharmaceutiques. Birkhäuser. 8 March 2013. pp. 407–. ISBN 978-3-0348-7059-7. https://books.google.com/books?id=ZSH3BwAAQBAJ&pg=PA407.