Chemistry:Trapidil
From HandWiki
Short description: Chemical compound
 | |
| Clinical data | |
|---|---|
| Trade names | Rocornal, Avantrin, Travisco |
| AHFS/Drugs.com | International Drug Names |
| Routes of administration | By mouth |
| ATC code | |
| Legal status | |
| Legal status |
|
| Identifiers | |
| |
| CAS Number | |
| PubChem CID | |
| ChemSpider | |
| UNII | |
| Chemical and physical data | |
| Formula | C10H15N5 |
| Molar mass | 205.265 g·mol−1 |
| 3D model (JSmol) | |
| |
| |
  (what is this?) (verify) | |
Trapidil is a vasodilator and an antiplatelet drug.[1][2] It also acts as an antagonist of platelet-derived growth factor.[3]
An analog was assigned the codename AR 12-456.[4]
References
- ↑ "Effect of trapidil, an antiplatelet and vasodilator agent on gentamicin-induced nephrotoxicity in rats". Pharmacological Research 44 (4): 321–328. October 2001. doi:10.1006/phrs.2001.0864. PMID 11592868.
- ↑ "Effect of trapidil in myocardial ischemia-reperfusion injury in rabbit". Indian Journal of Pharmacology 46 (2): 207–210. March–April 2014. doi:10.4103/0253-7613.129320. PMID 24741195.
- ↑ "Trapidil (triazolopyrimidine), a platelet-derived growth factor antagonist, reduces restenosis after percutaneous transluminal coronary angioplasty. Results of the randomized, double-blind STARC study. Studio Trapidil versus Aspirin nella Restenosi Coronarica". Circulation 90 (6): 2710–2715. December 1994. doi:10.1161/01.cir.90.6.2710. PMID 7994812.
- ↑ "Trapidil and other 5-triazolo-(1, 5-alpha)-pyrimidine derivatives as calcium channel blockers in 108CC5 cells". Biomedica Biochimica Acta 44 (5): K37–K41. 1985. PMID 2415119.
 |  |
