Chemistry:Sulfoxone

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Short description: Chemical compound
Sulfoxone
Skeletal formula of aldesulfone sodium
Space-filling model of the component ions of aldesulfone sodium
Clinical data
Routes of
administration
Oral
ATC code
Pharmacokinetic data
Protein binding69%
MetabolismHepatic
Elimination half-life3 to 8 hours
Identifiers
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEMBL
Chemical and physical data
FormulaC14H16N2Na2O6S3
Molar mass450.45 g·mol−1
3D model (JSmol)
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Sulfoxone or aldesulfone sodium is an anti-leprosy drug.[1] It is also known as diasone. Sulfoxone sodium was introduced in Japan in 1948.[2] Ernest Muir introduced it to Western use while serving as superintendent of the Chacachacare Leprosarium on Trinidad in the Caribbean.[3]

References

  1. "Sulfoxone". http://www.drugbank.ca/drugs/DB01145. 
  2. "[A 50-year history of new drugs in Japan: the developments of antileprosy drugs and their epidemiological aspects]". Yakushigaku Zasshi 37 (1): 76–83. 2002. PMID 12412600. 
  3. Browne, Stanley George (1974), "Ernest Muir, C.M.G., C.I.E., M.D. (Edin.), F.R.C.S., LL.D. 1880–1974", International Journal of Leprosy (Bauru: International Leprosy Association) 42 (4): pp. 457–458, PMID 4617724, http://ila.ilsl.br/pdfs/v42n4a14.pdf .