Chemistry:Remeglurant

From HandWiki
Short description: Chemical compound
Remeglurant
Remeglurant structure.png
Clinical data
Other namesMRZ-8456
ATC code
  • None
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC17H15BrN4O
Molar mass371.238 g·mol−1
3D model (JSmol)

Remeglurant (INN; developmental code name MRZ-8456) is a drug which acts as a selective antagonist of the mGlu5 receptor.[1][2][3] It is under development by Merz Pharmaceuticals for the treatment of drug-induced dyskinesia but no development has been reported since at least 2016.[3]

See also

References

  1. World Health Organization (2013). "International Nonproprietary Names for Pharmaceutical Substances (INN): Proposed INN: List 109". WHO Drug Information (World Health Organization) 27 (2). https://www.who.int/medicines/publications/druginformation/innlists/PL109.pdf. 
  2. Danysz W, Dekundy A, Hechenberger M, Henrich M, Jatzke C, Nagel J, Parsons CG, Weil T, Fotins J, Gutcaits A, Kalvinsh I, Zemribo R, Kauss V, "Substituted pyrazolo[1,5-A]pyrimidines as metabotropic glutamate receptor modulators.", US patent 7985753, issued 4 August 2006, assigned to Merz Pharmaceuticals GmbH
  3. 3.0 3.1 "Remeglurant". Adis Insight. Springer Nature Switzerland AG. http://adisinsight.springer.com/drugs/800045269.