Chemistry:Pirquinozol

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Short description: Chemical compound
Pirquinozol
Pirquinozol.svg
Clinical data
Routes of
administration
Oral
ATC code
  • none
Legal status
Legal status
  • In general: uncontrolled
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
Chemical and physical data
FormulaC11H9N3O2
Molar mass215.212 g·mol−1
3D model (JSmol)

Pirquinozol (SQ-13,847) is a drug which was investigated as an antiallergen and antiasthmatic agent in the early 1980s but was never marketed.[1][2][3] Notably, pirquinozol is not an antihistamine, though it does block the release of histamine evoked by allergens, and it does not bind to β-adrenergic receptors either.[1]

References

  1. 1.0 1.1 "Antiallergic properties of SQ 13,847, an orally effective agent. II. Activity in vitro". The Journal of Pharmacology and Experimental Therapeutics 213 (3): 437–40. June 1980. PMID 6162946. http://jpet.aspetjournals.org/cgi/pmidlookup?view=long&pmid=6162946. 
  2. "Antiallergic properties of SQ 13,847, an orally effective agent. I. Activity in vivo". The Journal of Pharmacology and Experimental Therapeutics 213 (3): 432–6. June 1980. PMID 7205610. http://jpet.aspetjournals.org/cgi/pmidlookup?view=long&pmid=7205610. 
  3. "Anti-allergic properties of pirquinozol (SQ 13,847) an orally effective agent. Evaluation in an anti-IgE-induced pulmonary function model in rats". The Journal of Pharmacy and Pharmacology 35 (6): 394–6. June 1983. doi:10.1111/j.2042-7158.1983.tb02967.x. PMID 6135784.