Chemistry:Fexuprazan

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Short description: Chemical compound


Fexuprazan
Abeprazan.svg
Clinical data
Trade namesFexuclue
Other namesAbeprazan; DWP14012; DWP-14012
ATC code
  • None
Legal status
Legal status
  • Rx in South Korea, Mexico
Identifiers
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
ChEMBL
Chemical and physical data
FormulaC19H17F3N2O3S
Molar mass410.41 g·mol−1
3D model (JSmol)

Fexuprazan (trade name Fexuclue) is a drug for the treatment of gastroesophageal reflux disease (GERD).[1] It is a potassium-competitive acid blocker.[2]

Fexuprazan is approved for use in South Korea and Mexico.[3][4]

References

  1. Ramani, Azaan; Merchant, Alisha; Cash, Brooks D. (2023). "Review of the clinical development of fexuprazan for gastroesophageal reflux–related disease". European Journal of Clinical Pharmacology 79 (8): 1023–1029. doi:10.1007/s00228-023-03521-4. PMID 37344679. 
  2. Kim, Gwang Ha; Choi, Myung-Gyu; Kim, Jin Il; Lee, Soo Teik; Chun, Hoon Jai; Lee, Kook Lae; Choi, Suk Chei; Jang, Jae-Young et al. (2023). "Efficacy and Safety of Fexuprazan in Patients with Acute or Chronic Gastritis". Gut and Liver 17 (6): 884–893. doi:10.5009/gnl220457. PMID 36789577. 
  3. "펙수클루정40밀리그램(펙수프라잔염산염)". https://nedrug.mfds.go.kr/pbp/CCBBB01/getItemDetail?itemSeq=202108192. 
  4. "Daewoong Pharma's GER drug gets product OK from Mexico". Korea Economic Daily. October 19, 2023. https://www.kedglobal.com/bio-pharma/newsView/ked202310190002.