Biology:ZSP1601

From HandWiki

ZSP1601 is an experimental pan-phosphodiesterase inhibitor developed by Guangdong Raynovent Biotech for nonalcoholic steatohepatitis.[1][2]

References

  1. Zhu, Xiaoxue; Wu, Min; Wang, Hong; Li, Haijun; Lin, Junjie; Peng, Yun; Hu, Yue; Li, Cuiyun et al. (4 May 2021). "Safety, tolerability, and pharmacokinetics of the novel pan-phosphodiesterase inhibitor ZSP1601 in healthy subjects: a double-blinded, placebo-controlled first-in-human single-dose and multiple-dose escalation and food effect study". Expert Opinion on Investigational Drugs 30 (5): 579–589. doi:10.1080/13543784.2021.1900822. PMID 33682556. 
  2. Hu, Yue; Li, Haijun; Zhang, Hong; Chen, Xiaoxin; Chen, Jinjun; Xu, Zhongyuan; You, Hong; Dong, Ruihua et al. (12 October 2023). "ZSP1601, a novel pan-phosphodiesterase inhibitor for the treatment of NAFLD, A randomized, placebo-controlled phase Ib/IIa trial" (in en). Nature Communications 14 (1): 6409. doi:10.1038/s41467-023-42162-0. ISSN 2041-1723. PMID 37828034. Bibcode2023NatCo..14.6409H.