Biology:Savolitinib

From HandWiki
Short description: Chemical compound
Savolitinib
Savolitinib.svg
Clinical data
Other namesVolitinib
Identifiers
CAS Number
ChemSpider
UNII
KEGG
Chemical and physical data
FormulaC17H15N9
Molar mass345.370 g·mol−1
3D model (JSmol)

Savolitinib is an experimental small molecule inhibitor of c-Met. It is being investigated for the treatment of cancer by AstraZeneca.[1] It is in phase II clinical trials for adenocarcinoma, non-small cell lung cancer, and renal cell carcinoma.[2] It has been given conditional approval for these indication in China.[3]

References

  1. "Savolitinib". Statement on a Nonproprietary Name Adopted by the USAN Council. American Medical Association. 26 October 2016. https://searchusan.ama-assn.org/usan/documentDownload?uri=%2Funstructured%2Fbinary%2Fusan%2Fsavolitinib.pdf. 
  2. "Savolitinib - AstraZeneca/Hutchison China MediTech Limited". AdisInsight. Springer Nature Switzerland AG. https://adisinsight.springer.com/drugs/800035893. 
  3. "Savolitinib: First Approval". Drugs 81 (14): 1665–1670. September 2021. doi:10.1007/s40265-021-01584-0. PMID 34455538. 

External links