Medicine:Treponematosis

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Treponematosis
SpecialtyInfectious disease

Treponematosis is a term used to individually describe any of the diseases caused by four members of the bacterial genus Treponema. The four diseases are collectively referred to as treponematoses:[1]

  • Syphilis (Treponema pallidum pallidum)
  • Yaws (Treponema pallidum pertenue)
  • Bejel (Treponema pallidum endemicum)
  • Pinta (Treponema carateum)

Traditional laboratory tests cannot distinguish the treponematoses.[2] However, sequence differences among the T. pallidum subspecies have been identified. Molecular approaches involving PCR to identify these sequences are being developed.[3]

References

  1. Giacani, L.; Lukehart, S. A. (2014). "The Endemic Treponematoses". Clinical Microbiology Reviews 27 (1): 89–115. doi:10.1128/CMR.00070-13. PMID 24396138. 
  2. "Endemic treponemal diseases". Transactions of the Royal Society of Tropical Medicine and Hygiene 108 (10): 601–7. October 2014. doi:10.1093/trstmh/tru128. PMID 25157125. 
  3. "Advances in the diagnosis of endemic treponematoses: yaws, bejel, and pinta". PLOS Neglected Tropical Diseases 7 (10): e2283. 2013. doi:10.1371/journal.pntd.0002283. PMID 24205410. 

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