File:Genetic-Modifiers-of-MeCP2-Function-in-Drosophila-pgen.1000179.s006.ogv

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Genetic-Modifiers-of-MeCP2-Function-in-Drosophila-pgen.1000179.s006.ogv ‎(file size: 1,008 KB, MIME type: application/ogg)

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Description
English: Neuronal specific overexpression of MeCP2 results in motor dysfunction. Flies aged 30 days after eclosion are shown in a climbing assay. After being tapped to the bottom of the vial, flies are given 18 seconds to climb past 7 cm, marked by a line on the tube. The control flies (left side, blue) show good climbing ability, while MeCP2 transgenic flies (right side, red) do not perform well.
Date
Source Video S1 from Cukier H, Perez A, Collins A, Zhou Z, Zoghbi H, Botas J (2008). "Genetic Modifiers of MeCP2 Function in Drosophila". PLOS Genetics. DOI:10.1371/journal.pgen.1000179. PMID 18773074. PMC: 2518867.
Author Cukier H, Perez A, Collins A, Zhou Z, Zoghbi H, Botas J
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