Chemistry:Apiol

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1944 advertisement for Ergoapiol

Apiol, also known as liquid apiol or green oil of parsley is the extracted oleoresin of parsley, rather than the distilled oil. Due to its similarity to the term apiole, care should be taken to avoid confusion.[1] Apiol is an irritant and, in high doses, it can cause liver and kidney damage.[2] Cases of death due to attempted abortion using apiol have been reported.[3][4]

Hippocrates wrote about parsley as a herb to cause an abortion.[5] Plants containing apiole were used by women in the Middle Ages to terminate pregnancies.[citation needed]

Its use was widespread in the US, often as ergoapiol or apergol, until a highly toxic adulterated product containing apiol and tri-ortho-cresyl phosphate (also famous as the adulterant added to Jamaican ginger) was introduced on the American market.[when?][citation needed]

Now that safer methods of abortion are available, apiol is almost forgotten.[citation needed]

References

  1. Shulgin, Alexander T. (April 1966). "Possible Implication of Myristicin as a Psychotropic Substance". Nature 210 (5034): 380–384. doi:10.1038/210380a0. PMID 5336379. Bibcode1966Natur.210..380S. 
  2. Amerio, A; De Benedictis, G; Leondeff, J; Mastrangelo, F; Coratelli, P (January 1968). "La nefropatia da apiolo" (in it). Minerva Nefrologica 15 (1): 49–70. OCLC 100396864. PMID 5736450. 
  3. Quinn, Louis J.; Harris, Cecil; Joron, Guy E. (15 April 1958). "Apiol Poisoning". Canadian Medical Association Journal 78 (8): 635–636. PMID 20325694. 
  4. Hermann, Kate; Le Roux, Anne; Fiddes, F.S. (June 1956). "Death from apiol used as abortifacient". The Lancet 267 (6929): 937–939. doi:10.1016/s0140-6736(56)91522-7. PMID 13320936. 
  5. Sage-Femme Collective (2008). Natural Liberty: Rediscovering Self-induced Abortion Methods. Natural Liberty. ISBN 978-0-9645920-0-1. [page needed]

Further reading