Chemistry:1-Bromo-3-chloropropane

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1-Bromo-3-chloropropane
BrCH2CH2CH2Cl.png
Names
Preferred IUPAC name
1-Bromo-3-chloropropane
Other names
Trimethylene chlorobromide
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
EC Number
  • 203-697-1
RTECS number
  • TX4113000
UNII
UN number 2688
Properties
C3H6BrCl
Molar mass 157.44 g·mol−1
Appearance Colorless liquid
Melting point −58.9 °C (−74.0 °F; 214.2 K)
Boiling point 143.3 °C (289.9 °F; 416.4 K)
Hazards
GHS pictograms GHS02: FlammableGHS06: ToxicGHS07: HarmfulGHS08: Health hazard
GHS Signal word Warning
H226, H302, H315, H319, H331, H332, H335, H341, H412
P201, P202, P210, P233, P240, P241, P242, P243, P261, P264, P270, P271, P273, P280, P281, P301+312, P302+352, P303+361+353, P304+312, P304+340, P305+351+338, P308+313, P311, P312, P321
Flash point 57 °C (135 °F; 330 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

1-Bromo-3-chloropropane is an organohalogen compound with the formula Br(CH2)3Cl. It is a colorless liquid, produced by free-radical addition of hydrogen bromide to allyl chloride.[1] It is used as an alkylating agent to install the –(CH2)3Cl[2] [3] and –(CH2)3– groups.[4] For example, it is a precursor to 4-chlorobutyronitrile.

References

  1. Dagani, M. J.; Barda, H. J.; Benya, T. J.; Sanders, D. C.. "Ullmann's Encyclopedia of Industrial Chemistry". Ullmann's Encyclopedia of Industrial Chemistry. Weinheim: Wiley-VCH. doi:10.1002/14356007.a04_405. 
  2. Allen, Charles F. H.; Domeier, L. A. (1928). "γ-Chlorobutyronitrile". Org. Synth. 8: 52. doi:10.15227/orgsyn.008.0052. 
  3. Evans, D. A.; Domeier, L. A. (1974). "Endocyclic Enamine Synthesis: N-Methyl-2-Phenyl-δ2-tetrahydropyridine". Org. Synth. 54: 93. doi:10.15227/orgsyn.054.0093. 
  4. Glass, D. B.; Weissberger, A. (1946). "Julolidine". Org. Synth. 26: 40. doi:10.15227/orgsyn.026.0040.