Biology:Uracil-5-carboxylate decarboxylase

From HandWiki
Short description: Class of enzymes
uracil-5-carboxylate decarboxylase
Identifiers
EC number4.1.1.66
CAS number59299-01-3
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

The enzyme uracil-5-carboxylate decarboxylase (EC 4.1.1.66) catalyzes the chemical reaction

uracil 5-carboxylate [math]\displaystyle{ \rightleftharpoons }[/math] uracil + CO2

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is uracil-5-carboxylate carboxy-lyase (uracil-forming). Other names in common use include uracil-5-carboxylic acid decarboxylase, and uracil-5-carboxylate carboxy-lyase.

References

  • "The enzymatic conversion of uracil 5-carboxylic acid to uracil and carbon dioxide". J. Biol. Chem. 245 (24): 6706–10. 1970. PMID 5482775.