Biology:TXNIP

From HandWiki
A representation of the 3D structure of the protein myoglobin showing turquoise α-helices.
Generic protein structure example

Thioredoxin-interacting protein is a protein that in humans is encoded by the TXNIP gene.[1][2]

Interactions

TXNIP has been shown to interact with Thioredoxin[3] and ZBTB32.[4]

Related gene problems

References

  1. "Isolation and characterization of a novel cDNA from HL-60 cells treated with 1,25-dihydroxyvitamin D-3". Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression 1219 (1): 26–32. Sep 1994. doi:10.1016/0167-4781(94)90242-9. PMID 8086474. 
  2. "Entrez Gene: TXNIP thioredoxin interacting protein". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10628. 
  3. "Identification of thioredoxin-binding protein-2/vitamin D(3) up-regulated protein 1 as a negative regulator of thioredoxin function and expression". The Journal of Biological Chemistry 274 (31): 21645–50. Jul 1999. doi:10.1074/jbc.274.31.21645. PMID 10419473. 
  4. "VDUP1 upregulated by TGF-beta1 and 1,25-dihydorxyvitamin D3 inhibits tumor cell growth by blocking cell-cycle progression". Oncogene 22 (26): 4035–46. Jun 2003. doi:10.1038/sj.onc.1206610. PMID 12821938. 

Further reading