Biology:TNRC6B

From HandWiki
Short description: Protein-coding gene in the species Homo sapiens


A representation of the 3D structure of the protein myoglobin showing turquoise α-helices.
Generic protein structure example

Trinucleotide repeat-containing gene 6B protein is a protein that in humans is encoded by the TNRC6B gene.[1]

Interactions

TNRC6B has been shown to interact with EIF2C2.[2] It is also known to associate with argonaute proteins and has been shown to be required for miRNA-guided gene silencing in HeLa cells.[3]

References

  1. "Entrez Gene: TNRC6B trinucleotide repeat containing 6B". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23112. 
  2. "A conserved motif in Argonaute-interacting proteins mediates functional interactions through the Argonaute PIWI domain". Nat. Struct. Mol. Biol. 14 (10): 897–903. October 2007. doi:10.1038/nsmb1302. PMID 17891150. 
  3. "Identification of novel argonaute-associated proteins". Curr. Biol. 15 (23): 2149–55. December 2005. doi:10.1016/j.cub.2005.10.048. PMID 16289642. 

Further reading