Biology:SL1 RNA

From HandWiki
SL1 RNA
RF00198.jpg
Predicted secondary structure and sequence conservation of SL1
Identifiers
SymbolSL1
RfamRF00198
Other data
RNA typeGene
Domain(s)Eukaryota
GO0000365
SO0000233
PDB structuresPDBe

This family represents the SL1 RNA. The gene encoding SL1 RNA is commonly, but not always, located in the spacer region between 5S-rRNA genes. The SL1 RNA is involved in trans-splicing, which is a form of RNA processing. The acquisition of a spliced leader from an SL RNA is an inter-molecular reaction that precisely joins exons derived from separately transcribed RNAs. This mechanism of mRNA maturation has been shown to occur in a number of lower eukaryotes and is commonplace in nematodes.[1]

References

  1. "Trans-spliced leader RNA, 5S-rRNA genes and novel variant orphan spliced-leader of the lymphatic filarial nematode Wuchereria bancrofti, and a sensitive polymerase chain reaction based detection assay". Gene 269 (1–2): 185–193. May 2001. doi:10.1016/S0378-1119(01)00438-3. PMID 11376950. 

External links