Biology:SAOUHSCs221
From HandWiki
| SAOUHSCs221 antisense RNA | |
|---|---|
 Predicted secondary structure and sequence conservation of SAOUHSCs221 | |
| Identifiers | |
| Symbol | SAOUHSCs221 |
| Alt. Symbols | art200, STnc490 |
| Rfam | XXXX |
| Other data | |
| RNA type | Gene; sRNA |
| Domain(s) | Bacteria |
| PDB structures | PDBe |
SAOUHSCs221 is a 108nt bacterial antisense RNA found by RNA-seq analysis in Staphylococcus aureus strain HG003 grown in rich medium,[1] strain JKD60008 [2] and strain NCTC8325.[3]
SAOUHSCs221 is expressed antisense to the IS200 transposase sequence, at the level of the 5’UTR sequence of the transposase ORF. Construction of this family only identified homologues in Firmicutes. However a small RNA named art200 (antisense regulator of transposase IS200) was also described E. coli and S. enterica (enterobacteria).[4]
References
- ↑ Liu W, Rochat T, Toffano-Nioche C, Le Lam TN, Bouloc P, Morvan C (2018). "Assessment of Bona Fide sRNAs in Staphylococcus aureus.". Front Microbiol 9: 228. doi:10.3389/fmicb.2018.00228. PMID 29515534.
- ↑ Howden BP, Beaume M, Harrison PF, Hernandez D, Schrenzel J, Seemann T (2013). "Analysis of the small RNA transcriptional response in multidrug-resistant Staphylococcus aureus after antimicrobial exposure.". Antimicrob Agents Chemother 57 (8): 3864–74. doi:10.1128/AAC.00263-13. PMID 23733475.
- ↑ Carroll RK, Weiss A, Broach WH, Wiemels RE, Mogen AB, Rice KC (2016). "Genome-wide Annotation, Identification, and Global Transcriptomic Analysis of Regulatory or Small RNA Gene Expression in Staphylococcus aureus.". mBio 7 (1): e01990-15. doi:10.1128/mBio.01990-15. PMID 26861020.
- ↑ Ellis MJ, Trussler RS, Haniford DB (2015). "A cis-encoded sRNA, Hfq and mRNA secondary structure act independently to suppress IS200 transposition.". Nucleic Acids Res 43 (13): 6511–27. doi:10.1093/nar/gkv584. PMID 26044710.
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