Biology:Ribonuclease IV

From HandWiki
Ribonuclease IV
Identifiers
EC number3.1.26.6
CAS number61536-76-3
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

Ribonuclease IV (EC 3.1.26.6, endoribonuclease IV, poly(A)-specific ribonuclease) is an enzyme.[1][2] This enzyme catalyses the following chemical reaction

Endonucleolytic cleavage of poly(A) to fragments terminated by 3'-hydroxy and 5'-phosphate groups

This enzyme forms oligonucleotides with an average chain length of 10.

References

  1. "Endoribonuclease IV. A poly(A)-specific ribonuclease from chick oviduct. 1. Purification of the enzyme". European Journal of Biochemistry 70 (1): 241–8. November 1976. doi:10.1111/j.1432-1033.1976.tb10975.x. PMID 1009928. 
  2. "Endoribonuclease IV. 2. Further investigation on the specificity". European Journal of Biochemistry 70 (1): 249–58. November 1976. doi:10.1111/j.1432-1033.1976.tb10976.x. PMID 1009929. 

External links