Biology:Putidaredoxin—NAD+ reductase

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Putidaredoxin—NAD+ reductase
Identifiers
EC number1.18.1.5
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

Putidaredoxin—NAD+ reductase (EC 1.18.1.5, putidaredoxin reductase, camA (gene)) is an enzyme with systematic name putidaredoxin:NAD+ oxidoreductase.[1][2][3][4][5][6][7] This enzyme catalyses the following chemical reaction

reduced putidaredoxin + NAD+ [math]\displaystyle{ \rightleftharpoons }[/math] oxidized putidaredoxin + NADH + H+

Putidaredoxin—NAD+ reductase requires FAD.

References

  1. "Purification and properties of putidaredoxin reductase". The Journal of Biological Chemistry 258 (4): 2593–8. February 1983. PMID 6401738. 
  2. "Cloning and nucleotide sequences of NADH-putidaredoxin reductase gene (camA) and putidaredoxin gene (camB) involved in cytochrome P-450cam hydroxylase of Pseudomonas putida". Journal of Biochemistry 106 (5): 831–6. November 1989. PMID 2613690. 
  3. "Putidaredoxin reductase and putidaredoxin. Cloning, sequence determination, and heterologous expression of the proteins". The Journal of Biological Chemistry 265 (11): 6066–73. April 1990. PMID 2180940. 
  4. "Putidaredoxin reductase, a new function for an old protein". The Journal of Biological Chemistry 277 (28): 25831–9. July 2002. doi:10.1074/jbc.m201110200. PMID 12011076. 
  5. "Crystal structure of putidaredoxin, the [2Fe-2S] component of the P450cam monooxygenase system from Pseudomonas putida". Journal of Molecular Biology 333 (2): 377–92. October 2003. doi:10.1016/j.jmb.2003.08.028. PMID 14529624. 
  6. "Crystal structure of putidaredoxin reductase from Pseudomonas putida, the final structural component of the cytochrome P450cam monooxygenase". Journal of Molecular Biology 336 (4): 889–902. February 2004. doi:10.1016/j.jmb.2003.12.067. PMID 15095867. 
  7. "Structure of C73G putidaredoxin from Pseudomonas putida". Acta Crystallographica Section D 60 (Pt 5): 816–22. May 2004. doi:10.1107/s0907444904003348. PMID 15103126. https://zenodo.org/record/1236096/files/article.pdf. 

External links