Biology:Phytoene desaturase (3,4-didehydrolycopene-forming)

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Phytoene desaturase (3,4-didehydrolycopene-forming)
Identifiers
EC number1.3.99.30
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

Phytoene desaturase (3,4-didehydrolycopene-forming) (EC 1.3.99.30, 5-step phytoene desaturase, five-step phytoene desaturase, phytoene desaturase (ambiguous), Al-1) is an enzyme with systematic name 15-cis-phytoene:acceptor oxidoreductase (3,4-didehydrolycopene-forming).[1][2] This enzyme catalyses the following chemical reaction

15-cis-phytoene + 5 acceptor [math]\displaystyle{ \rightleftharpoons }[/math] all-trans-3,4-didehydrolycopene + 5 reduced acceptor (overall reaction)
(1a) 15-cis-phytoene + acceptor [math]\displaystyle{ \rightleftharpoons }[/math] all-trans-phytofluene + reduced acceptor
(1b) all-trans-phytofluene + acceptor [math]\displaystyle{ \rightleftharpoons }[/math] all-trans-zeta-carotene + reduced acceptor
(1c) all-trans-zeta-carotene + acceptor [math]\displaystyle{ \rightleftharpoons }[/math] all-trans-neurosporene + reduced acceptor
(1d) all-trans-neurosporene + acceptor [math]\displaystyle{ \rightleftharpoons }[/math] all-trans-lycopene + reduced acceptor
(1e) all-trans-lycopene + acceptor [math]\displaystyle{ \rightleftharpoons }[/math] all-trans-3,4-didehydrolycopene + reduced acceptor

This enzyme is involved in carotenoid biosynthesis.

See also

References

  1. "A single five-step desaturase is involved in the carotenoid biosynthesis pathway to beta-carotene and torulene in Neurospora crassa". Fungal Genetics and Biology 30 (2): 147–53. July 2000. doi:10.1006/fgbi.2000.1212. PMID 11017770. 
  2. "Novel apocarotenoid intermediates in Neurospora crassa mutants imply a new biosynthetic reaction sequence leading to neurosporaxanthin formation". Fungal Genetics and Biology 45 (11): 1497–505. November 2008. doi:10.1016/j.fgb.2008.09.001. PMID 18812228. 

External links