Biology:Phenylacetaldehyde dehydrogenase
From HandWiki
| phenylacetaldehyde dehydrogenase | |||||||||
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| Identifiers | |||||||||
| EC number | 1.2.1.39 | ||||||||
| CAS number | 58943-37-6 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a phenylacetaldehyde dehydrogenase (EC 1.2.1.39) is an enzyme that catalyzes the chemical reaction
- phenylacetaldehyde + NAD+ + H2O [math]\displaystyle{ \rightleftharpoons }[/math] phenylacetate + NADH + 2 H+
The 3 substrates of this enzyme are phenylacetaldehyde, NAD+, and H2O, whereas its 3 products are phenylacetate, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is phenylacetaldehyde:NAD+ oxidoreductase. This enzyme participates in phenylalanine metabolism and styrene degradation.
References
- "Metabolism of phenylalanine (Achromobacter eurydice). III Phenylacetaldehyde dehydrogenase". Methods Enzymol. 17A: 593–596. 1970. doi:10.1016/0076-6879(71)17245-x.
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