Biology:Mycoredoxin

From HandWiki
Short description: Class of enzymes
Mycoredoxin
Identifiers
EC number1.20.4.3
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

Mycoredoxin (EC 1.20.4.3, Mrx1, MrxI) is an enzyme with systematic name arseno-mycothiol:mycoredoxin oxidoreductase.[1] This enzyme catalyses the following chemical reaction

arseno-mycothiol + mycoredoxin [math]\displaystyle{ \rightleftharpoons }[/math] arsenite + mycothiol-mycoredoxin disulfide

Reduction of arsenate is part of a defense mechanism of the cell against toxic arsenate.

References

  1. "Arsenate reductase, mycothiol, and mycoredoxin concert thiol/disulfide exchange". The Journal of Biological Chemistry 284 (22): 15107–16. May 2009. doi:10.1074/jbc.m900877200. PMID 19286650. 

External links