Biology:Methylecgonone reductase
From HandWiki
| Methylecgonone reductase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 1.1.1.334 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Methylecgonone reductase (EC 1.1.1.334, MecgoR (gene name)) is an enzyme with systematic name ecgonine methyl ester:NADP+ oxidoreductase.[1] This enzyme catalyses the following chemical reaction
- ecgonine methyl ester + NADP+ [math]\displaystyle{ \rightleftharpoons }[/math] ecgonone methyl ester + NADPH + H+
The enzyme from the plant Erythroxylum coca participates in the biosynthesis of cocaine.
References
- ↑ "Plant tropane alkaloid biosynthesis evolved independently in the Solanaceae and Erythroxylaceae". Proceedings of the National Academy of Sciences of the United States of America 109 (26): 10304–9. June 2012. doi:10.1073/pnas.1200473109. PMID 22665766. Bibcode: 2012PNAS..10910304J.
External links
- Methylecgonone+reductase at the US National Library of Medicine Medical Subject Headings (MeSH)
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