Biology:L-serine-phosphatidylethanolamine phosphatidyltransferase

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L-serine-phosphatidylethanolamine phosphatidyltransferase
Identifiers
EC number2.7.8.29
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

L-serine-phosphatidylethanolamine phosphatidyltransferase (EC 2.7.8.29, phosphatidylserine synthase 2, serine-exchange enzyme II, PTDSS2 (gene)) is an enzyme with systematic name L-1-phosphatidylethanolamine:L-serine phosphatidyltransferase.[1][2] This enzyme catalyses the following chemical reaction

L-1-phosphatidylethanolamine + L-serine [math]\displaystyle{ \rightleftharpoons }[/math] L-1-phosphatidylserine + ethanolamine

This enzyme catalyses replacement of a polar head group of phosphatidylethanolamine with L-serine.

References

  1. "Cloning and expression of murine liver phosphatidylserine synthase (PSS)-2: differential regulation of phospholipid metabolism by PSS1 and PSS2". The Biochemical Journal 342 (1): 57–64. August 1999. doi:10.1042/0264-6021:3420057. PMID 10432300. 
  2. "Purification and characterization of human phosphatidylserine synthases 1 and 2". The Biochemical Journal 418 (2): 421–9. March 2009. doi:10.1042/bj20081597. PMID 19014349. 

External links