Biology:KDM1B
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 Generic protein structure example |
Lysine (K)-specific demethylase 1B is a protein that in humans is encoded by the KDM1B gene.[1]
Function
Flavin-dependent histone demethylases, such as KDM1B, regulate histone lysine methylation, an epigenetic mark that regulates gene expression and chromatin function.[1][2]
References
- ↑ 1.0 1.1 "Entrez Gene: Lysine (K)-specific demethylase 1B". https://www.ncbi.nlm.nih.gov/gene/221656.
- ↑ "A novel mammalian flavin-dependent histone demethylase". The Journal of Biological Chemistry 284 (26): 17775–82. Jun 2009. doi:10.1074/jbc.M109.003087. PMID 19407342.
Further reading
- "The ubiquitin carboxyl hydrolase BAP1 forms a ternary complex with YY1 and HCF-1 and is a critical regulator of gene expression". Molecular and Cellular Biology 30 (21): 5071–85. Nov 2010. doi:10.1128/MCB.00396-10. PMID 20805357.
- "Human LSD2/KDM1b/AOF1 regulates gene transcription by modulating intragenic H3K4me2 methylation". Molecular Cell 39 (2): 222–33. Jul 2010. doi:10.1016/j.molcel.2010.07.008. PMID 20670891.
- "KDM1B is a histone H3K4 demethylase required to establish maternal genomic imprints". Nature 461 (7262): 415–8. Sep 2009. doi:10.1038/nature08315. PMID 19727073. Bibcode: 2009Natur.461..415C.
- "The deubiquitinating enzyme BAP1 regulates cell growth via interaction with HCF-1". The Journal of Biological Chemistry 284 (49): 34179–88. Dec 2009. doi:10.1074/jbc.M109.046755. PMID 19815555.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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