Biology:D-lactate dehydratase

From HandWiki
D-lactate dehydratase
Identifiers
EC number4.2.1.130
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

D-lactate dehydratase (EC 4.2.1.130, glyoxylase III) is an enzyme with systematic name (R)-lactate hydro-lyase.[1][2] This enzyme catalyses the following chemical reaction

(R)-lactate [math]\displaystyle{ \rightleftharpoons }[/math] methylglyoxal + H2O

The enzyme converts methylglyoxal to (R)-lactate.

References

  1. "Glyoxalase III from Escherichia coli: a single novel enzyme for the conversion of methylglyoxal into D-lactate without reduced glutathione". The Biochemical Journal 305 (3): 999–1003. February 1995. doi:10.1042/bj3050999. PMID 7848303. 
  2. "Hsp31 of Escherichia coli K-12 is glyoxalase III". Molecular Microbiology 81 (4): 926–36. August 2011. doi:10.1111/j.1365-2958.2011.07736.x. PMID 21696459. 

External links