Biology:CorA metal ion transporter

From HandWiki
CorA-like Mg2+ transporter protein
PDB 2bbj EBI.jpg
Structure of the CorA Mg2+ transporter.[1]
Identifiers
SymbolCorA
PfamPF01544
InterProIPR002523
TCDB1.A.35
OPM superfamily66
OPM protein2bbj
CDDcd11744

The CorA transport system is the primary Mg2+ influx system of Salmonella typhimurium and Escherichia coli.[2][3] CorA is ubiquitous in the Bacteria and Archaea. There are also eukaryotic members of the family localized to the mitochondrial membrane such as MRS2 and Lpe10 in yeast.

Subfamilies

Human proteins containing this domain

MRS2L;

References

  1. "Crystal structure of the CorA Mg2+ transporter". Nature 440 (7085): 833–7. April 2006. doi:10.1038/nature04642. PMID 16598263. Bibcode2006Natur.440..833L. 
  2. "The CorA magnesium transporter gene family". Microb. Comp. Genom. 3 (3): 151–169. 1998. doi:10.1089/omi.1.1998.3.151. PMID 9775386. 
  3. "The CorA Mg2+ transport protein of Salmonella typhimurium. Mutagenesis of conserved residues in the third membrane domain identifies a Mg2+ pore". J. Biol. Chem. 273 (44): 28663–28669. 1998. doi:10.1074/jbc.273.44.28663. PMID 9786860. 

Further reading

  • "The CorA magnesium transporter gene family". Microb. Comp. Genom. 3 (3): 151–69. 1998. doi:10.1089/omi.1.1998.3.151. PMID 9775386. 
  • "The CorA Mg2+ transport protein of Salmonella typhimurium. Mutagenesis of conserved residues in the third membrane domain identifies a Mg2+ pore". J. Biol. Chem. 273 (44): 28663–9. October 1998. doi:10.1074/jbc.273.44.28663. PMID 9786860. 
  • "The nuclear gene MRS2 is essential for the excision of group II introns from yeast mitochondrial transcripts in vivo". J. Biol. Chem. 267 (10): 6963–9. April 1992. doi:10.1016/S0021-9258(19)50522-1. PMID 1551905. 
This article incorporates text from the public domain Pfam and InterPro: IPR002523