Biology:Calicivirin
From HandWiki
| Calicivirin | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.4.22.66 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Calicivirin (EC 3.4.22.66, Camberwell virus processing peptidase, Chiba virus processing peptidase, Norwalk virus processing peptidase, Southampton virus processing peptidase, norovirus virus processing peptidase, calicivirus trypsin-like cysteine protease, calicivirus TCP, calicivirus 3C-like protease, calicivirus endopeptidase, rabbit hemorrhagic disease virus 3C endopeptidase) is an enzyme.[1][2][3][4][5] This enzyme catalyses the following chemical reaction
- Endopeptidase with a preference for cleavage when the P1 position is occupied by Glu- and the P1- position is occupied by Gly-
Viruses that are members of the genus Norovirus (family Caliciviridae) are a major cause of epidemic acute viral gastroenteritis.
References
- ↑ "Calicivirus endopeptidases". Handbook of Proteolytic Enzymes (2nd ed.). London: Elsevier. 2004. pp. 1380–1382.
- ↑ "3C-like protease of rabbit hemorrhagic disease virus: identification of cleavage sites in the ORF1 polyprotein and analysis of cleavage specificity". Journal of Virology 69 (11): 7159–68. November 1995. PMID 7474137.
- ↑ "Processing of rabbit hemorrhagic disease virus polyprotein". Journal of Virology 70 (2): 1261–5. February 1996. PMID 8551592.
- ↑ "Polyprotein processing in Southampton virus: identification of 3C-like protease cleavage sites by in vitro mutagenesis". Journal of Virology 70 (4): 2605–10. April 1996. PMID 8642693.
- ↑ "Identification of further proteolytic cleavage sites in the Southampton calicivirus polyprotein by expression of the viral protease in E. coli". The Journal of General Virology 80 ( Pt 2) (2): 291–6. February 1999. doi:10.1099/0022-1317-80-2-291. PMID 10073687.
External links
- Calicivirin at the US National Library of Medicine Medical Subject Headings (MeSH)
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