Biology:CYP18 family

From HandWiki
Short description: Group of cytochrome P450 enzymes

Cytochrome P450, family 18, also known as CYP18, is an animal cytochrome P450 family found in insect genomes.[1] It is involved in insecticide resistance.[2] The first member gene identified was CYP18A1, from a Drosophila melanogaster fly, acting as a dimethylnitrosamine demethylase.[3]

References

  1. Nelson, DR (November 1998). "Metazoan cytochrome P450 evolution.". Comparative Biochemistry and Physiology. Part C, Pharmacology, Toxicology & Endocrinology 121 (1–3): 15–22. doi:10.1016/s0742-8413(98)10027-0. PMID 9972448. 
  2. Jin, Y; Gao, Y; Zhang, H; Wang, L; Yang, K; Dong, H (January 2020). "Detoxification enzymes associated with butene-fipronil resistance in Epacromius coerulipes.". Pest Management Science 76 (1): 227–235. doi:10.1002/ps.5500. PMID 31150148. 
  3. Bassett, MH; McCarthy, JL; Waterman, MR; Sliter, TJ (4 July 1997). "Sequence and developmental expression of Cyp18, a member of a new cytochrome P450 family from Drosophila.". Molecular and Cellular Endocrinology 131 (1): 39–49. doi:10.1016/s0303-7207(97)00093-2. PMID 9256362.