Biology:CBMAR
| Content | |
|---|---|
| Description | Beta-lactamase database annotating beta-lactamase based on their characteristics |
| Data types captured | Beta-lactamase |
| Organisms | Bacteria |
| Contact | |
| Primary citation | PMID 25475113 |
| Access | |
| Website | 14 |
| Miscellaneous | |
| Bookmarkable entities | yes |
CBMAR otherwise known as Comprehensive β-lactamase Molecular Annotation Resource is a database focused on the annotation and discovery of novel beta-lactamase genes and proteins in bacteria.[1] Beta-lactamases are characterized on CBMAR using the Ambler Classification system.[2] CBMAR organizes beta-lactamases according to their classes: A, B, C, and D. They are then further categorized by their (i) sequence variability, (ii) antibiotic resistance profile, (iii) inhibitor susceptibility, (iv) active site, (v) family fingerprints, (vi) mutational profile, (vii) variants, (viii) gene location, (ix) phylogenetic tree, etc. The primary sources of database for CBMAR are GenBank and Uniprot.[3] CBMAR is built on an Apache HTTP Server 2.2.17 with MySQL Ver 14.14 and hosted on Ubuntu 11.04 Linux platform.
See also
References
- ↑ Srivastava, Abhishikha; Singhal, Neelja; Goel, Manisha; Virdi, Jugsharan Singh; Kumar, Manish (2014-01-01). "CBMAR: a comprehensive β-lactamase molecular annotation resource" (in en). Database 2014: bau111. doi:10.1093/database/bau111. ISSN 1758-0463. PMID 25475113.
- ↑ Ambler, R. P. (1980-05-16). "The Structure of <latex>$\beta$</latex>-Lactamases". Philosophical Transactions of the Royal Society B: Biological Sciences 289 (1036): 321–331. doi:10.1098/rstb.1980.0049. ISSN 0962-8436. PMID 6109327.
- ↑ The UniProt Consortium (2011-11-18). "Reorganizing the protein space at the Universal Protein Resource (UniProt)". Nucleic Acids Research 40 (D1): D71–D75. doi:10.1093/nar/gkr981. ISSN 0305-1048. PMID 22102590.
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